In the era of the Industrial Revolution 4.0 and Society 5.0 plus pandemic COVID-19 as it is today, education in Indonesia has developed drastically by the implementation of MBKM Program. MBKM Program was a freedom of learning in campus environment of Indonesia that made the learning process is more flexible and according to student needs and demands. The learning process at Universitas Kristen Maranatha (UKM) has been developed by having Maranatha Online Learning (MORNING) system combined with MBKM Program. The purpose of this study is to describe the effectiveness of the implementation of MBKM Program from Science Major Departments at Universitas Kristen Maranatha, Indonesia. A set of questionnaires has been set up to analyze the implementation of MBKM Program in study area. The results showed that majority of lecturers, students and academic workers are interested to participate the MBKM Program. However, there is an opportunity to improve the increase of MBKM campaign activities both from government and internal university. The MBKM program provides challenges and opportunities for the development of innovation, creativity, capacity, personality, and student needs. Through ability requirements, real problems, social interaction, collaboration, self-management, performance demands, targets, and achievements, it is expected that a well-designed and implemented MBKM program, students' hard skills and soft skills will be formed strongly.