The 13-15 year old male smoker increased from 23.4% in 2007 to 29.3% in 2013. Meanwhile, the age of the initial smoker begin to shift from 15-24 years to 10-14 years. To anticipate the rate of increase in the number of smokers, especially in the younger generation, the Indonesian Government has obliged tobacco companies to include Pictorial Health Warnings (PHW) on the cigarette packaging they produce. PHW is an image contained in cigarette packaging that contains about smoking can causes cancer of the mouth, throat, lungs/bronchitis chronic; death, and endanger small children. This study aims to identify characteristics, knowledge, and perception of non-smoker teenagers to PHW and the relationship between variables. The study design was cross-sectional with non-smoking male teen research population of 2,473 people. As for the sample of 219 people selected by stratified random sampling. The research variables are characteristic, knowledge, and perception toward PHW. Data analysis used Chi-squared for bivariate and logistic regression for multivariate. The results showed 86.8% respondents had good knowledge and 71.7% had very good perception about PHW although 69.9% of their parents were smokers. There is a significant relationship between knowledge and perception of PHW in non-smoker teenagers.