This study has purposed to explain the effect of occupational safety and health programs on job satisfaction and employee performance. Wisma atlit development project with PT Brantas Abipraya kemayoran (Persero) as the main contractor where employees deal 9directly with the construction activities that may be directly affected of job risk. This study uses a quantitative approach to explanation research methods (explanatory research). Data collection techniques in the study using a questionnaire. The population in this study amounted to 65. The sampling method used is saturated samples so 9that the entire population is a sample. This research 9uses descriptive analysis and path analysis. The results of this study indicate that there is significant influence safety program on job satisfaction. There is a significant effect of occupational health programs on job satisfaction. There is a significant influence on the performance of safety program. There is a significant influence on the performance of occupational health programs. There is a significant influence on the performance of job satisfaction. Programs occupational safety and health has more influence on satisfaction rather than on performance and greater influence of occupational safety and health program on the performance rather than the influence of job satisfaction on performance.